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Fertile hopes in Kandy
By Kishanie S. Fernando
Sub-fertility can be a devastating experience changing every aspect of a person's life, one's self-esteem, dreams for the future and relationships with others. Few experiences are as challenging and overwhelming. Yet attention is mostly focused on the physical and not the emotional aspects of the problem.

Fully-equipped theatre

Sub-fertility is the inability to conceive after one year of unprotected intercourse or the inability to carry a pregnancy to term.

When a couple initially experience difficulties in conceiving, concerns replace anticipation and questions like what if they never have children, could they be impotent etc, begin to haunt them. Many couples initially deny the possibility of a problem. However once realization and acceptance are reached that they may need medical treatment, they experience an even more stressful, invasive and expensive period in their lives.

Because infertility is such a personal and private issue many couples do not share this experience with friends and family resulting in them suffering intensely and feeling isolated.

The ICSI machine

In Sri Lanka there are no support groups unlike in some countries and it is a lonelier struggle within a traditionally critical society. However there is some relief for persons having access to the Internet where there are many informative websites on fertility problems, latest medications, methods of treatment, even home remedies and support groups.

The greatest news for these couples is the new breakthroughs in sub-fertility treatments, which however require specialized lab tests, regular monitoring and a specialised team of doctors working in hi-tech medical environments.

As such the crucial decision is the choice of your doctor. A fertility specialist is an obstetrician-gynaecologist with advanced education, research and professional skills in reproductive endocrinology. However, it is equally important that the doctor has adequate time to listen to you, and explain to you his treatment plan.

The doctor must also be backed by a clinic with staff/technicians able to carry out specialised tests. The clinic should be equipped with up-to-date instruments like trans-vaginal ultrasound scanners. For eg. treatment with clomid or injectable fertility medication requires routine monitoring by this equipment. The clinic ideally should also provide access to a specialised team of consultants such as reproductive endocrinologists, embryologists, laparoscopic surgeons, reproductive urologists etc.

Therefore, the success rate in sub-fertility treatment may vary depending on a combination of factors including doctors' skills and experience, up-to-date lab facilities and instruments and ultimately the cause of infertility and the woman's age. Experts advise that one should carefully assess any infertility treatment centre before undergoing treatment.

A new IVF (In Vitro Fertilisation) laboratory complete with modern state of the art facilities, as an expansion to the Ferticare Medical Centre now offers hope to patients in Peradeniya. This is the brainchild of Obstetrician-Gynaecologist Dr. Neil Senawiratne, conceived after 17 years of practice with special emphasis in advanced management of sub-fertility in the UK and in the government and private sectors of Sri Lanka.

Dr. Senawiratne is chairman of Ferticare Medical Centre, Peradeniya and Gynaecare Medical Centre, Kurunegala. He was the first to introduce to Sri Lanka in 1994, the trans vaginal ultrasound scan which can monitor follicle development and assess the thickness of the lining and abnormalities of the uterus, detect fibroids and ovarian cysts etc, without invasive surgery. He was also the first to get down a complete laparoscopic surgical unit including diagnostic and surgical ability and since 1997 manages a gynaecological endoscopic unit in Kandy.

Dr. N. Lekamge, the coordinator of the team is an obstetrician-gynaecologist, endocrinologist and pharmacologist. The Gujarat-born Dr. Himanshu Patel, is a consultant embryologist to 15 hospitals across India.

The team also consists of a third obstetrician-gynaecologist, consultant anaesthetist, consultant reproductive urologist, two other doctors who will act as counsellors, and a qualified laboratory technician.

Both Dr. Senawiratne and Dr. Lekamge trained under Professor Mahasara Gunaratne who set up the first infertility clinic in Peradeniya 30 years ago. Commenting on Intra Uterine Insemination (IUI) performed with unprepared sperm by some doctors today, Dr. Senawiratne said that this dangerous procedure, banned in developed countries, may cause infections and subsequent infertility due to tubal blocks. There are even a few reported cases of anaphylaxis, he said.

He said that another harmful treatment still carried out by some doctors is the outdated ovarian wedge resection which leads to adhesions around the ovaries resulting in subsequent sub-fertility.

Ferticare is dedicated to the introduction of new concepts like fertility fitness. According to Dr. Lekamge, this concept much in vogue in UK and Australia is new to Sri Lanka and involves pre-conception counselling where an assessment on fertility could be made advising the couple whether conception should/should not be postponed. Advice is also given on the use of contraceptives, folic acid supplements, diabetes, epilepsy etc. and weight loss programmes in view of conception. According to Dr. Lekamge many sub-fertility problems today can be treated beneficially by hi-tech treatment procedures known as Assisted Reproductive Techniques like IVF. However, Dr. Senawiratne stressed that IVF is never the first step in the treatment of infertility but reserved for cases where other methods like fertility drugs, surgery and IUIs have not resulted in pregnancy.

The new centre has a modern theatre, ICSI machine by which a single sperm is injected into an egg to increase the chance of fertilization and thus develop an embryo in keeping with the IVF procedure. (This infinitesimal procedure involves the egg being held by a pipette which is 20 times thinner than a human hair and sperm injected to by a pipette which is 60 times thinner than a human hair. The egg itself is no bigger than the tip of a pen.), facilities for freezing embryos and sperm (sperm bank), Lamina floors, carbon dioxide incubators etc.

The key criteria is the maintenance of a germ-free environment giving maximum support for the handling of eggs and sperm, said Dr. Lekamge.

However the staggering cost of an IVF sadly restricts the number of couples who could afford it. Dr. Lekamge sets it out as an approximate Rs. 300,000 for one cycle while explaining that 80% of the cost is on instruments, culture media and drugs. However subsequent implantation by frozen embryos may drastically reduce the cost.

How effective is such procedure? Dr. Senawiratne said the cumulative pregnancy rate is higher with fresh eggs. The prohibitive cost of IVF treatment makes one wonder why the government cannot assist as in the case of other organ transplants.


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