| Medical 
 Reducing 
              menopausal difficulties Is hormone replacement therapy a solution for women 
              suffering from severe cases of menopause? Esther Williams finds 
              out
 
 
              
                | 
 Click 
                    image for a larger view |   'To 
              take estrogen or not to take estrogen.' The subject has stimulated 
              so much debate that women approaching menopause are unsure of what 
              action to take in view of the contradictory information available. 
              While some studies show that this potent hormone can ward off many 
              age-related ailments, it also suggests the increase in chances of 
              getting breast cancer.
  When women 
              reach the age of 45 - 50, their ovaries gradually produce lower 
              levels of estrogen before stopping altogether. It is the last stage 
              of a biological process, a transition between a woman's childbearing 
              years and her non-childbearing years called menopause. Women who 
              have had surgery to remove both their ovaries experience surgical 
              menopause, when hormone production and menstruation stop immediately. 
              
  Estrogen and 
              other female sex hormones such as progesterone and testosterone 
              are involved in the development and maintenance of secondary sex 
              characteristics such as breasts and affect many aspects of women's 
              physical and emotional health. 
  According to 
              Prof. Harsha Seneviratne, "Estrogen is a hormone that makes 
              women what they are. Manufactured primarily by the ovaries, it is 
              a natural hormone that develops female characteristics such as voice, 
              skin texture, genital tracts and the female psyche itself. Women 
              tend to lose all those when they stop producing estrogen."
  At this point, 
              most women experience menopausal symptoms such as hot flashes, night 
              sweats, insomnia, irritation, anxiety, forgetfulness, depression 
              and lack of concentration. There are other signs too. All of a sudden 
              women seem to develop high cholesterol, high blood pressure or osteoporosis. 
              A couple of decades ago, women suffered these symptoms in silence 
              and accepted them as part of life or the ageing process. "It 
              did not matter those days when life expectancy was around 55 years 
              for a woman. Life expectancy for an average Sri Lankan woman now 
              is 74 years," Prof. Seneviratne says.
  "With 
              one third of her life ahead of her, a woman is capable of doing 
              many things. By taking HRT, she can be assured of a better quality 
              of life," says Dr. Ranjith Almeida (gynaecologist) who practises 
              at Asha Central Hospital and Castle Street Hospital.
  "Modern 
              day women need not resign themselves to this when there is a remedy 
              available."
  Menopausal 
              symptoms cause much agony. Even with the A.C. on, women break out 
              in a cold sweat, experience hot flushes and suffer from various 
              vaginal infections. Many also suffer from back pain. From a simple 
              fall or the smallest impact, women are known to break bones.
  Emotional health 
              is also affected. Acute mood swings, lack of energy, fatigue and 
              depression are common. Metabolism changes and slows down. They can 
              just look at food and put on weight and are also more prone to heart 
              attacks.
  "People 
              on insulin cannot do without it. Similarly, the lack of estrogen 
              can cause much distress and therefore needs to be replaced," 
              explains Dr. Seneviratne. Today, gynaecologists in Sri Lanka recommend 
              Hormone Replacement Therapy (HRT) for women suffering from severe 
              symptoms of menopause. "They can benefit from the replacement 
              of these female hormones."
  "The obvious 
              repercussions of not taking estrogen on a short-term basis are hot 
              flushes, profuse sweating and an effect on brain functions (depression, 
              anxiety, etc.) which can be very distressing, although they may 
              not apply to all. On a long term basis, bones lose their calcium 
              and no amount of calcium intake can replace the loss. This may lead 
              to hip fracture, bent spine (hunch), spine fracture, etc. Further, 
              all pelvic organs and support ligaments are dependent on estrogen 
              for integrity and activity. These include the female genital tract 
              and urinary system. Women with cholesterol are also known to benefit 
              from estrogen," Dr. Seneviratne continues.
  What are the 
              benefits? Estrogen has been proved to be very effective in treating 
              menopausal symptoms. It can certainly reduce those immediate symptoms 
              like hot flushes, sleeplessness and vaginal dryness. It may improve 
              mood and psychological wellbeing in women, their behaviour and sleep 
              patterns. There are other reports stating that estrogen prevents 
              memory loss, delays the onset of Alzheimer's disease, prevents colon 
              and bowel cancer and improves urinary incontinence.
  HRT involves 
              treatment with estrogen alone or in combination with progestin. 
              This compensates for the decrease in natural hormones that occurs 
              at menopause. Women who have had their uterus removed are given 
              estrogen alone, whereas women with a uterus take a combination of 
              estrogen plus progestin.
  What of the 
              side-effects? There are thousands of web sites that highlight the 
              adverse effects - breast cancer, cardiovascular disease, uterine 
              cancer, etc. These results indicate that the risks of long-term 
              estrogen with progestin outweigh the benefits.
  HRT sounds 
              like a risky proposition. How safe is it? Most gynaecologists think 
              it is a necessary solution to evade the agonising effects of menopause. 
              
  Explaining 
              that some, possibly because of a healthy lifestyle 'age gracefully' 
              while others have a traumatic time, Dr. Nalini Prasad, gynaecologist 
              of Apollo Hospital says, "HRT should be tailormade for women 
              after balancing the risks and benefits. The risk factor varies from 
              woman to woman depending on their genetics, the environment they 
              were brought up in, their lifestyle and family history of health 
              problems and therefore cannot be generalised."
  Patients are 
              counselled and advised of the pros and cons of taking HRT and are 
              encouraged to take the treatment with a specialist's approval and 
              under medical supervision.
  "Cancer 
              can occur in women who are on HRT. But the incident is only slightly 
              higher than three in a thousand. We cannot predict it. You can still 
              get cancer even if you do not take HRT. You may die of high blood 
              pressure or stroke, you may fall and fracture a bone caused by low 
              estrogen levels. We know for sure that women who take estrogen, 
              do not get infarcts," says another gynaecologist.
  Most drugs 
              have adverse effects, the gynaecologists say. Even the common aspirin 
              is known to cause stomach ulcers. The risk of taking HRT however, 
              can be overcome by regular routine breast examinations or pap smears, 
              ultra sounds and endometrial biopsy (DNC) once every two years, 
              thereby detecting any cancer in its earliest stage and commencing 
              treatment that in most cases can cure a person. (To be continued)
 On 
              the floor, on a trolleyVijaya 
              Jayasuriya relates his experiences as a patient of the Cardiology 
              Unit of the National Hospital
 It was with a sense of natural apprehension that 
              I stepped into the country's leading cardiology unit attached to 
              the National Hospital (CU) as a heart patient for a test called 
              Coronary Angiogram (CA).
 
  All distinctions 
              of social hierarchy blurred into a very facile nonentity as I had 
              to sleep all three days without a bed, two days on the ward floor 
              desperately trying to cushion the knocks of my ageing bones on concrete 
              with a mat provided to all and sundry by a seemingly considerate 
              yet voluble male attendant. The day spent on a trolley was the biggest 
              trauma, for, following the CA - just out of the theatre - you were 
              supposed to stay put without even turning your leg lest the slit 
              made on your crotch to insert a tube into an artery might open up 
              by the slightest movement or jerk making you bleed profusely. 
  Lying on your 
              back on the metal surface of a trolley for nearly 10 hours was agony 
              for me. Specially since all eight other people, some thirty or thirty-five 
              year olds among them taken for the same test that day being lucky 
              enough to get a bed. However, I tremendously enjoyed the camaraderie 
              among the patients with social ranks merging into nothingness, despite 
              all difficulties. 
  Having declared 
              that I would require by-pass surgery, I was sent a day after the 
              CA to see a surgeon at the OPD. Four of us jostled into an ambulance 
              by a youthful yet arrogant attendant, we arrived there to wait with 
              a milling crowd under a low asbestos roof heated like an oven - 
              ideal conditions for a weak heart patient like me - only to find 
              that the surgeon had not turned up and only his assistants were 
              there which meant that you would be put to a ward there until the 
              day the big man comes.
  After consulting 
              the doctor, we sat on the now empty benches as the crowd diminished 
              with the evening and were waiting for our conveyance when somebody 
              arrived to call it a day ordering us out and locking up the place. 
              Now, minus even a bench to slump down on and dead beat too, we, 
              the four victims of licensed lethargy hung on, resting our haunches 
              on the brick paving of a building for nearly one hour waiting to 
              be taken back to our ward.
  The nurses 
              at the CU however were doing a thorough job of work to treat and 
              keep the patients in comfort as far as possible and this much is 
              commendable apart from the young set of doctors attached to the 
              wards who proved to be kind-hearted gentlemen so far as their duty 
              was concerned.
  On the operating 
              table, a young doctor performed the CA on me puncturing an artery 
              on my crotch. They applied a liquid profusely over that area and 
              then started inserting the tube. Immediately I could feel the pain. 
              No one asked me if I could feel or not, as the private dentist would 
              ask you about the injection before he pulls out your tooth. I jerked 
              my leg in pain only to be met with a stern warning of more pain 
              if repeated. When later I asked a partner in adversity he told me 
              surprisingly that he had not felt anything at all, and it was a 
              different surgeon who had done his CA. Is there an individual factor 
              involved in whether you are severely dealt with or not, on the operating 
              table?
  In a cubicle 
              outside the theatre it is a veritable pantomime enacted by some 
              attendants (or are they nurses?) to plug the flow of blood from 
              my injury. They dabbed it with a thick wad of wool and kept pressing 
              upon it with both hands. Using their full body weight, they removed 
              the wad and if it still flowed repeated the same procedure several 
              times taking about 20 minutes. My problem was that I had a slight 
              swelling on probably a gland on my crotch which at least the doctor 
              should have noticed before puncturing the place. So the pain was 
              excruciating when the young fellow was pressing on the very place 
              with his full body weight and I had no choice but to undergo the 
              ordeal in silence.
  But these drawbacks 
              apart, the wards of the unit prove to be a place akin to heaven 
              except for a few inevitable shortcomings. I saw even in small hours 
              of the night female nurses come running to patients who begin to 
              shout in pain and provide them with whatever was necessary. Even 
              the doctors made several rounds in the dead of night to attend to 
              a patient who had taken a bad turn. 
  The meals were 
              tolerable with two or three curries while the standards of sanitation 
              was kept at a fairly high level - the ward floor was regularly mopped 
              and it was the fault of patients themselves that often created problems 
              - for instance, clogging the sinks with food particles in spite 
              of having a bin.
  I believe that 
              the CU is run according to some principles to do with the actual 
              conditions governing a heart patient who deserves to be dealt with 
              tenderly as he is more prone to anxiety and tension than an ordinary 
              one. The staff therefore appears to have been well-trained accordingly, 
              not to cause unnecessary mental stress for them. There are however 
              two issues requiring discreet handling; firstly, getting the patients 
              to sign the document undertaking to bear the risk involved in CA 
              is only kept open to those who can read English well, lest only 
              plebeians will try to make a scene if risks are made clear to them. 
              The second point that should improve is the obvious favours rendered 
              on grounds of attachment which is anyway inevitable and therefore 
              those at the receiving end should not try to make a show of it. 
              If these aspects are improved, the Cardiology Unit would be rated 
              much better than any of its much - vaunted private counterparts. 
               Peace 
              and quiet for the hopelessThe only hospice we have in Sri 
              Lanka, Shantha Sevana, situated near the Cancer Hospital in Maharagama, 
              is like an oasis of tranquillity for suffering people. Those who 
              have visited the Cancer Hospital will best appreciate the contrast 
              it offers. Here is a place that is pleasant, clean and airy, with 
              a limited number of beds and nurses and attendants who provide the 
              kind of care those awaiting death need.
 
  There are two 
              wards, each having 16 beds - the one for males is downstairs and 
              the female ward is upstairs. There are also two rooms to accommodate 
              patients who come with a carer to stay with them. The kitchen is 
              clean and shining. The toilets are well kept. The bed 1inen looked 
              fresh and clean and the patients appeared well cared for. The nursing 
              Sister who showed us round, Sister Pannala, seemed dedicated to 
              her work. With long service in government hospitals behind her, 
              and a stint at the Royal Marsden Hospital in England, she had taken 
              early retirement and then opted to serve here. While the nurses 
              I saw were on the elderly side, the attendants, both male and female, 
              were youthful. There is also a team of volunteers who visit the 
              patients on a regular basis, but we did not meet any on that particular 
              day.
  I spoke to 
              a patient who was sitting on his bed with his legs dangling down. 
              He was Mr. Appuhamy who appeared to have cancer of the mouth, for 
              he could only speak from one corner of it. He said he had been in 
              the hospice for 1 l/2 years, after a long stay at the Cancer Hospital, 
              and he was fortunate to be able to end his days in a place like 
              this. He had no family, friends nor relatives to visit him, yet 
              was cheerful and uncomplaining. 
  Moving on, 
              I came to the bed of a man with a big, greying moustache and a ready 
              smile and only one leg. There were crutches leaning on the wall 
              beside his bed. He was Mr. Subramaniam from Wattala and he had children 
              who often visited him. He told us that he had been promised an artificial 
              limb by some society at the Gangaramaya and he was awaiting that. 
              I winced when he volunteered to take off the bandage round his stump, 
              but he cheerfully undid it and told us how, after the original amputation, 
              a further portion had to be cut off. It has now healed completely 
              and he looks forward to getting the new limb and learning to walk 
              with it. He even talked of going home, but I learned privately from 
              the Sister that it was more likely he would remain at Shantha Sevana 
              because, although he didn't seem to be aware of it, he was a terminally 
              ill patient, like all the others in the hospice. 
  In the female 
              ward upstairs, we were drawn to the bedside of a patient who had 
              bunches of gaily-coloured artificial flowers on her bed. She, Karunawathie, 
              spends most of her time making these flowers and sells them to visitors. 
              It was something she had learned while in domestic service. Karunawathie 
              had suffered from a brain tumour and was blind when she was admitted 
              to the Cancer Hospital. After surgery to remove the tumour, she 
              got partial sight - just enough to enable her to engage herself 
              in this therapeutic occupation which she enjoys and which also brings 
              her a modest income. She told us that one of the volunteers buys 
              the required materials for her. Everyone of us was glad to buy a 
              bunch of Karunawathie's pretty flowers priced at Rs. 10 per flower.
  Seelawathie, 
              paralysed on one side, sits up in bed making drawings, using pastels 
              and this is obviously occupational therapy for her. Sometimes, the 
              nurses pin up her work on the wall beside her and this makes her 
              happy. Several of the patients were out in the hall, listening to 
              a bana sermon being given by a monk, preceding a dhana that a benefactor 
              was giving the patients that day. That must be how we missed meeting 
              Malkanthi. This lady has lost her husband and only child and now, 
              stricken with cancer, she bravely carries on and finds some meaning 
              to her days in teaching English to the young nurse-aides.
  We met only 
              one patient who was in tears. This lady had been brought to Shantha 
              Sevana from Trincomalee only the day before and must have felt strange 
              and lonely in the unfamiliar surroundings because she spoke only 
              Tamil and therefore couldn't communicate by word with nurses or 
              fellow-patients. She cheered up considerably when one of our group 
              who knew Tamil, spent a little time chatting with her and listening 
              to her.
  The three young 
              nurse-aides have one off day a week and 21 days privilege leave 
              for a year. I asked them whether they didn't find it depressing 
              to care for terminally ill patients, some of whom were in constant 
              pain. They smiled and said "No" and one of them, Chandima 
              Ratnayake, spoke for all three when she said in Sinhala, "This 
              is merit-earning work."
  In a passage, 
              I saw a large board on which the meals donated for each day are 
              written down, along with the names of the donors. I noticed that 
              breakfast for on that particular day had been 'donated by Miss Chandima 
              Ratnayake in loving memory of her father.' I was touched that this 
              young girl had been moved to give Rs. 350 out of her hard-earned 
              money (we later enquired from the office about the amount required 
              for different meals). We were also told that two items often in 
              short supply are milk powder and sugar and that gifts of these are 
              always welcome. 
  Only the terminally 
              ill are admitted to Shantha Sevana, so a letter from a consultant 
              recommending admission is essential. It's absolutely free of charge. 
              If well-to-do patients come in, they may make a voluntary donation 
              if they wish, but they are not asked to make any payment for services 
              rendered. No treatment is given at the hospice, for that part is 
              over for those who come here. A doctor visits the patients regularly 
              and pain-killers are given to those who need them and they are kept 
              as comfortable as possible. 
  We were surprised 
              that there were a few vacant beds. Vacancies do occur, of course, 
              as and when terminally ill patients die, but I would have expected 
              there to be a long waiting list and that vacant beds would be immediately 
              snapped up. I asked Ms. Perin Captain about this and she too was 
              dismayed that this didn't always happen and wondered herself why 
              it was so. This hospice was Perin's dream which the Captain family 
              helped her to fulfil. I attended its formal opening by Prime Minister 
              Sirimavo Bandaranaike in 1996 and she said it was a place that would 
              meet a felt need.
  Shantha Sevana 
              gives hope to people who might feel hopeless after the long and 
              painful process of being treated for cancer. I don't mean the hope 
              of recovery, but hope of some quality of life during the months 
              or years that are left to them. I noticed pictures on the walls, 
              television in the ward, fish tanks, a well-tended garden with stone 
              benches. To destitute and lonely people, particularly, a haven such 
              as this where they meet with kindness and tender care and can die 
              in clean and pleasant surroundings, with decency and dignity, must 
              make a world of difference. - Anne Abayasekara
 Symposium 
              on Asthma A Symposium on Varied Aspects of Bronchial Asthma will be 
              held on Sunday, November 17 at the Colombo Hilton. The symposium 
              has been organised by the Respiratory Disease Study Group. 22 Specialist 
              speakers will make presentations. Doctors are requested to telephone 
              695418, 05522483 for further particulars.
 
  The presentations 
              will be as follows: Current scenario in asthma - Dr. Kirthi Gunasekera, 
              Inflammatory mechanisms and airway remodelling - Dr. Manela Joseph, 
              Natural history and clinical spectrum - Dr. A. T. Munasinghe, Allergens, 
              immunology and immunotherapy - Dr. Anura Weerasinghe, Recent developments 
              in occupational asthma - Ms. K. N. Lankathilaka, Clinical studies 
              in asthma - Dr. Rajitha Wickremasinghe, Diagnostic difficulties 
              in asthma - Dr. J.H.L Cooray, Acute, severe asthma - Dr. Shyam Fernando, 
              Ventilatory strategies in asthma - Dr. Vajira Tennekoon, Conventional 
              pharmacotherapy - Dr. Bandu Gunasena and Inhaled cortcosteroids 
              - Dr. B. J. C. Perera.
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